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Ultimately, whether a 280mm radiator can be installed on the floor of a computer case depends on several factors. The size of the case, dimensions of the radiator, compatibility with liquid cooling, and available space all play a role in determining if the radiator can be installed in this configuration. It is crucial to research specific cases, consult their specifications, and take accurate measurements to ensure a proper fit and efficient liquid cooling system. Only by considering these factors can one determine if a radiator with a size of 280mm can be successfully installed on the floor of a computer case.